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Sepsis and coagulation Christian Fenger-Eriksen Center for Haemophilia and Thrombosis, Department of Anaesthesiology, Aarhus University Hospital, Denmark
Treatment of hemorrhage Restoration of blood volume & oxygen delivery Five approaches Blood Oxygen carrying plasma expanders (blood substitutes) Crystalloids Colloids ...
... cause movement of water into cells Hypertonic movement of water from cells Crystalloids contain electrolytes; used for fluid volume replacement Colloids plasma expanders ...

... blood, agglutination will occur between the agglutinin and the corresponding agglutinogens Positive reactions indicate agglutination Blood Typing Plasma Volume Expanders ...
... require human donors Fluids and Electrolytes: Blood Products (cont'd) Increase COP and PV Pull fluid from extravascular space into intravascular space (plasma expanders ...
Interventions: Fat emboli Prevent: recognize, immobilize, hydrate O2 therapy Steroids Fluid volume replacement Plasma expanders Monitoring Complications of Fractures ...
... fibrin formation (rbc’s can be caught up and appears as clumping) Increased serum proteins (Multiple Myeloma, etc.), infusion of high molecular weight plasma expanders ...
Plasma Volume Expanders. Plasma expanders. Have osmotic properties that directly increase fluid volume. Are used when plasma is not available. Examples: purified human serum ...
Used as volume or plasma expanders They include: Albumin Hetastarch Dextran Blood It is given as packed RBCs, which should be cross-matched, but in an urgent ...
... PO fluids, liberal) Switch to D5 when plasma glucose is bellow 250 mg/dl Watch BP, pulse, BUN/creatinine and urinary output and adjust if necessary Use plasma expanders ...
... fluid (50 l); note::: plasma protein binding tissue sequestration Distribution into body compartments Plasma 3.5 litres, heparin, plasma expanders ...
... prohibited by IOC Drugs Stimulants, opioids, anabolic agents, diuretics, peptide hormones Methods Blood doping, artificial oxygen administration, plasma expanders ...
Lost plasma should be replaced early with an electrolyte solution, plasma, or plasma expanders to prevent or treat reduced blood volume (hypovolemic) shock.
... of dextrose that can be administered in peripheral IV Provides 340 kcal/L Free water Limit of dextrose concentration may be infused peripherally Plasma Expanders Stay in ...
Plasma Expanders. Dextran which is a long chain polysaccharide. Solutions are confined to the vascular compartment and preferentially expand this portion of the ECF.
... after 1 hr , stop Neostigmine Supportive Therapy RESPIRATORY FAILURE : ABG Intubate & Ventilate Neostigmine & Atropine HYPOTENSION : Plasma expanders ...
Narcotic antagonists and plasma expanders have limited indications in newborn resuscitation Sodium bicarbonate is not recommended in the immediate postnatal period if ...
Diuretics and other masking agents Diuretics Epitestosterone Probenecid α-reductase inhibitors Plasma expanders Prohibited Methods M1. Enhancement of oxygen transfers ...
... All UN SMs and other personnel must have access to disposable syringes and needles All UN SMs and other personnel must have access to safe blood and plasma expanders UN ...
... of choice, with diuretics being given to prevent recurrence Administration of albumin may be appropriate Large volume paracentesis without the use of plasma expanders can ...
The incidence and/or severity of anaphylaxis to radiocontrast media, Hymenoptera stings, neuromuscular agents, and plasma expanders are greater in adults than in children.
... Blood volume replacement should be performed cautiously using: - concentrated erythrocytes, to obtain a hemoglobin level of about 70–80 g/L - plasma expanders ...
Serum from patients with altered albumin-to-globulin ratios (e.g., patients with multiple myeloma) or who have received high-molecular-weight plasma expanders (e.g ...
... of glucose units formed by many microorganisms commercially used Leuconostic mesenteroides converts sucrose -> α 1,6 glucose dextrans Used as blood plasma expanders ...
... Plasma Substitutes; Use of whole blood is considered to be a waste of resources Blood Transfusion Red Blood Cells Platelets Granulocytes Fresh Frozen Plasma (FFP ...

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